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Effectiveness of zinc in modulating perinatal effects of arsenic on the teratological effects in mice offspring Biol. Res.
Ahmad,Mohammad; Wadaa,Mohammad A. M; Farooq,Muhammad; Daghestani,Maha H; Sami,Ahmed S.
Exposure to arsenic via drinking water is considered as a worldwide problem. Studies have shown that arsenic exposure during pregnancy affects embryogenesis and offspring development in rats and mice. Zinc as a micronutrient regulates many physiological functions, including an antioxidative role under various toxic conditions. However, studies on the perinatal protective effect of zinc on offspring need further attention. The present study was designed to evaluate the potential protective role of zinc in mitigating the adverse effects in the offspring of arsenic exposure during pregnancy. The arsenic (40mg/kg body weight) and zinc (4% w/v) doses formed the only drinking fluid source for the experimental groups of dams during the perinatal period of the...
Tipo: Journal article Palavras-chave: Arsenic; Zinc; Perinatal; Mice offspring; Sensory motor reflexes; Behavior; Oxidative stress.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000200003
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